A pilot study of the use of placental cord blood samples in monitoring for mutational events.
نویسندگان
چکیده
A pilot study exploring the examination of placental cord blood samples for mutant proteins with one-dimensional electrophoretic techniques is described. Although technical advances are such that the techniques employed in this study are now partially superceded, the practical problems encountered in this study would be typical of any monitoring program of this type. No mutations altering electrophoretic mobility among a battery of 51 different locus products were encountered in a total of 277,747 locus tests. When these data are combined with similar data from other studies, the mutation rate for electromorphs becomes 0.34 X 10(-5)/locus/generation.
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ورودعنوان ژورنال:
- Mutation research
دوره 204 3 شماره
صفحات -
تاریخ انتشار 1988